General Cell Based Assays
Discovery Life Sciences Gentest Human Hepatocytes
Gentest Human Hepatocyte Cryopreserved 3D Spheroid Qualified 5 0x10e6 cells
Eurofins Discoverx PathHunter Human GPR6 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR6 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR6 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Activin B (ACVR1C/ACVR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Activin B (ACVR1C/ACVR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of ACVR1C/ACVR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Discovery Life Sciences Gentest CD 1 Mouse Hep
Gentest CD 1 Mouse Hepatocytes Plateable Inducible Grade Female
Eurofins Discoverx PathHunter Human VEGF (KDR/KDR) Dimerization Cell-Based Assay Kit (HEK 293)
The PathHunter Human VEGF (KDR/KDR) Stable Cell Line Dimerization Assay (HEK 293) measures ligand-induced dimerization of KDR/KDR. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress ADRB2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0182E2CP0L)
The PathHunter ADRB2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB2 and EA-tagged β-Arrestin-2. Activation of ADRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human AFP ASY
The R-PLEX Human AFP Assay from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for the quantitative measurement of alpha-fetoprotein (AFP) in human serum plasma and tissue culture supernatant This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide a highly sensitive and reproducible method for detecting AFP an important biomarker used to help diagnose and monitor hepatocellular carcinoma and other malignancies as well as fetal defects The assay has a wide dynamic range of 1 95-2000 pg/mL and requires only 50 L of sample
Discovery Life Sciences Gentest Sprague DawlRat Hep
Gentest Sprague Dawley Rat Hepatocytes Cryopreserved Female Plateable Inducible
Eurofins Discoverx PathHunter eXpress GPR109B CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0791E2CP2M)
The PathHunter GPR109B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. 3-hydroxyoctanoic acid) based activation of GPR109B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR109B and EA-tagged β-Arrestin-2. Activation of GPR109B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EphB3 Functional Assay, 10-Plate Kit. (93-0842E3CP16L)
The PathHunter eXpress EphB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB3 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PTGER3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0640E2CP0L)
The PathHunter PTGER3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin E2) based activation of PTGER3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGER3 and EA-tagged β-Arrestin-2. Activation of PTGER3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam SIRT2 Activity Assay Kit (Fluorometric)
SIRT2 Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress TYK2 Activity Assay, 2-Plate Kit. (93-0875E3CP16M)
The PathHunter eXpress TYK2 Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the TYK kinase domain. The cell line is engineered to express the catalytic domain from TYK2 fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the TYK2 catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter IL17RA/IL17RC Dimerization Bioassay Kit, 2pl. (93-0999Y3-00053)
The PathHunter IL17RA/IL17RC Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-17) induced dimerization of IL17RA/IL17RC receptors. This product uses EFC technology. The cell line included overexpresses IL17RC target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL17RA/IL17RC, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Abcam Thrombin Activity Assay Kit (Fluorometric)
Thrombin Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement