General Cell Based Assays
Meso Scale Discovery R-PLEX Mouse Fractalkine ASY
The R-PLEX Mouse Fractalkine Assay from Meso Scale Discovery is a multiplex immunoassay that measures Fractalkine levels in mouse biological samples such as serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescence detection technology and is provided in a convenient 96-well plate format The assay has high sensitivity and wide dynamic range A proprietary diluent is provided for optimal sample dilution Each kit provides sufficient reagents to assay one 96-well plate This quantitative assay provides accurate and reproducible results with minimal sample volume requirements It offers a streamlined workflow and rapid results
Eurofins Discoverx PathHunter eXpress GPR146 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0365E2ACP1L)
The PathHunter GPR146 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR146 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR146 and EA-tagged β-Arrestin-2. Activation of GPR146 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GRPR Activated GPCR Internalization Assay, 2-Plate Kit. (93-0667E3CP5M)
The PathHunter GRPR Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of GRPR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged GRPR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting GRPR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mVIPR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0619E2MCP2L)
The PathHunter mVIPR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. VIP) based activation of mVIPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mVIPR1 and EA-tagged β-Arrestin-2. Activation of mVIPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 10,000 Assay Points
Meso Scale Discovery R-PLEX Rat KC/GRO ASY
The R-PLEX Rat KC/GRO Assay from Meso Scale Diagnostics is a multiplex immunoassay kit for measuring rat keratinocyte chemoattractant (KC) and growth-regulated oncogene (GRO) in various samples It uses electrochemiluminescence (ECL) and MSD s MULTI-ARRAY technology offering high sensitivity and a wide dynamic range The kit includes a 96-well plate with specific capture antibodies detection antibodies and calibrators Results are read on MSD platforms and analyzed with MSD Discovery Workbench software enabling efficient analysis of these neutrophil chemoattractants
Eurofins Discoverx cAMP Hunter LHCGR Bioassay Kit, 2-Plate. (95-0106Y2-00137)
The cAMP Hunter CHO-K1 LHCGR Bioassay Kit provides a robust, and highly sensitive functional, cell-based assay to measure drug potency and detect neutralizing antibodies.. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
American Research Products Inc Fish SuperoXide Dismutase SOD
Fish SuperoXide Dismutase (SOD) ELISA kit from CUSABIO Detection Range 1 25 ng/mL-20 ng/mL Sensitivity 0 625 ng/mL Sample serum plasma tissue homogenates Method Competitive
Eurofins Discoverx PathHunter eXpress PTAFR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0236E2CP0L)
The PathHunter PTAFR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTAFR and EA-tagged β-Arrestin-2. Activation of PTAFR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology CNR1 Rabbit pAb
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
ABclonal Technology LTB4R Rabbit pAb
Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.
Cayman Chemical Glycerol CellBased Assay Kit
Cayman’s Glycerol Cell-Based Assay provides a convenient tool for studying triglycerides/fatty acid cycling and its regulation in adipocytes or hepatocytes. This kit will allow investigators to screen compounds involved in lipid storage and metabolism. Chloroquine is included in the kit as a positive control for screening pharmaceuticals that induce lipid droplet accumulation and free glycerol release from hepatocytes.
Eurofins Discoverx cAMP Hunter eXpress AGTRL1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0147E2CP2L)
The cAMP Hunter AGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of AGTRL1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type AGTRL1, a naturally Gi/Go coupled GPCR. Upon activation of AGTRL1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human TREM2 Detection Kit, 10,000 Assay Points
HTRF Human TREM2 Detection Kit, 10,000 Assay Points